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Don Cheadle & George Clooney

Actor Don Cheadle is also an activist for the end of genocide in Darfur. He founded the charitable organization Not On Our Watch (and co-authored a book by the same name) along with George Clooney, Brad Pitt and Matt Damon. Their mission is to focus global attention and resources towards putting an end to genocide and mass atrocities around the world. (AP Photo/Damian Dovarganes)

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Brangelina Love them or hate them, you have to admit that the media maelstrom known as Brangelina has used their combined star wattage - and star fundage - for great good. They've donated millions of dollars to charitable organizations like Doctors Without Borders as well as building sustainable housing for Katrina victims in New Orleans. (AP Photo/Brennan Linsley)
Lance Armstrong Speaking of love... romancer of Hollywood stars, seven-time Tour de France winner and cancer survivor Lance Armstrong has helped raised millions to help those affected by cancer and support cancer research through his eponymous foundation.
Selena Gomez They call her the new Miley, but so far Disney star Selena Gomez has not posed for any racy photo spreads. She also wears a 'promise ring' as a symbol of her chastity.
Jonas Brothers Despite the zillions of young women throwing themselves at these young musicians, the Jonas Brothers also wear promise rings to remind them of their pledge of chastity. Nick Jonas (right) is rumored to be dating Selena Gomez and they reportedly 'bonded' over their rings. (AP Photo/Reinhold Matay, file)
Bono He has a few years on the Jonas boys, but fellow musician Bono has become a prominent activist for third-world debt relief and raising awareness of the plight of Africa's AIDS pandemic.
Hayden Panettier... She's barely legal, but Hayden Panettiere has already gotten arrested for her cause - trying to save dolphins from being slaughtered in Japan. She's also the spokesperson for voting organization Declare Yourself.
Oprah Winfrey Talk show host Oprah is famous for her philanthropy, from her 'Angel Network' to founding a school for girls in South Africa, Oprah's generosity - and millions - have touched the lives of many.
Bette Midler Chanteuse Bette Midler, shown here at her annual 'Hulaween' gala, has been an environmental advocate for years. The event is a benefit for Midler's New York Restoration Project, which reclaims, restores, and develops under-resourced open spaces in New York City's five boroughs. (AP Photo/Stuart Ramson)
Miley Cyrus Yeah, there were those risque Vanity Fair photos. And that not-so-nice YouTube video mocking fellow Disney star Selena Gomez, but if that's the worse that Miley does, she'll still be a role model. She's still a big hero to a lot of little girls.
Sharon Stone So Sharon Stone is more famous for her "Basic Instinct" maneuver than her charity work, but she has helped AMFAR raise millions as the chairman of their campaign for AIDS research. (Photo: Universal)
Natalie Portman Aside from just being a class act, unlike many of her peers, actress Natalie Portman is actively involved in several charities including acting as co-chair for the 'Village Banking Campaign,' a financial assistance program offering microloans to entrepreneurs in the world's poorest countries. (AP Photo/Andrew Medichini)
Michael J. Fox Actor Michael J. Fox, who has Parkinson's Disease, has used his illness to raise awareness through his Michael J. Fox Foundation for Parkinson's, which has funded over $120 million in research since its inception. (AP Photo/Charles Krupa)
Don Cheadle & Ge... Actor Don Cheadle is also an activist for the end of genocide in Darfur. He founded the charitable organization Not On Our Watch (and co-authored a book by the same name) along with George Clooney, Brad Pitt and Matt Damon. Their mission is to focus global attention and resources towards putting an end to genocide and mass atrocities around the world. (AP Photo/Damian Dovarganes)
Audrey Hepburn Hepburn was known for her spectacular fashion sense, but her work for UNICEF - starting in the 1950s and continuing until her death in 1993 - was what really made her beautiful inside and out. The Hollywood icon was on the receiving end of UNICEF's help as a child in the Netherlands during the German occupation in World War II and she never forgot it. (AP Photo)
Bob Hope Veteran TV and film actor Bob Hope spent over 50 years working with the USO, performing for troops stationed overseas in wartime during World War II, the Korean War, the Vietnam War and the Persian Gulf War. Hope was named an 'Honorary Veteran' by an Act of Congress in 1997 for his half century of selfless work. (Photo: Paul Hesse)

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